{ "spec_version": "0.1.0-draft", "tolerance_years": 0.01, "vectors": [ { "id": "endurance-woman-41", "note": "Spec example persona: trained woman, SBP and eGFR not measured.", "person": { "age": 41.3, "sex": "female", "meta": { "vo2max_source": "lab" }, "inputs": { "vo2max_ml_kg_min": 44.0, "hrr_1min_bpm": 28, "resting_hr_bpm": 54, "rmssd_ms": 58, "night_resp_rate_per_min": 14.8, "sleep_hours": 6.8, "sri_0_100": 74, "hba1c_pct": 5.4, "fasting_glucose_mg_dl": 91, "waist_to_height": 0.47, "hs_crp_mg_l": 1.2, "grip_kg": 26, "strength_min_per_week": 15, "steps_per_day": 8900, "sedentary_hours": 10.4, "mvpa_min_per_day": 45, "drinks_per_week": 9, "smoking_status": "never" } }, "expected": { "spec_version": "0.1.0-draft", "chronological_age": 41.3, "estimate": 36.04, "offset_years": -5.26, "range": [ 31.77, 40.32 ], "range_level": 0.8, "contributions_years": { "alcohol": 0.5, "crp": 0.0, "glycemia": 0.0, "grip": 0.692, "hr_recovery": -0.15, "hrv_low": 0.0, "resp_rate": 0.0, "resting_hr": -0.8, "sedentary": 0.561, "sleep_duration": 0.341, "sleep_regularity": 2.648, "smoking": 0.0, "steps": -1.287, "strength_training": -1.483, "vo2max": -6.281, "waist_to_height": 0.0 }, "domains_years": { "fitness": -6.431, "habits": -0.226, "heart": -0.8, "metabolic": 0.0, "sleep": 2.989, "strength": -0.791 }, "missing_key_signals": [ "systolic_bp", "egfr" ] } }, { "id": "average-woman-41", "note": "Average values for age and sex must score about zero.", "person": { "age": 41.0, "sex": "female", "inputs": { "vo2max_ml_kg_min": 30.4, "hrr_1min_bpm": 25, "resting_hr_bpm": 70, "sleep_hours": 7.5, "sri_0_100": 81, "hba1c_pct": 5.3, "fasting_glucose_mg_dl": 92, "waist_to_height": 0.5, "hs_crp_mg_l": 1.0, "grip_kg": 28.85, "strength_min_per_week": 0, "steps_per_day": 6500, "sedentary_hours": 9.5, "mvpa_min_per_day": 20, "drinks_per_week": 5, "smoking_status": "never" } }, "expected": { "spec_version": "0.1.0-draft", "chronological_age": 41.0, "estimate": 41.05, "offset_years": 0.05, "range": [ 37.67, 44.44 ], "range_level": 0.8, "contributions_years": { "alcohol": 0.0, "crp": 0.0, "glycemia": 0.0, "grip": 0.017, "hr_recovery": 0.0, "resting_hr": 0.0, "sedentary": 0.0, "sleep_duration": 0.0, "sleep_regularity": 0.0, "smoking": 0.0, "steps": 0.0, "strength_training": 0.0, "vo2max": 0.037, "waist_to_height": 0.0 }, "domains_years": { "fitness": 0.037, "habits": 0.0, "heart": 0.0, "metabolic": 0.0, "sleep": 0.0, "strength": 0.017 }, "missing_key_signals": [ "systolic_bp", "egfr" ] } }, { "id": "former-smoker-man-67", "note": "Older man, quit at 50, measured BP and eGFR, wearable VO2max.", "person": { "age": 67.0, "sex": "male", "meta": { "vo2max_source": "wearable" }, "inputs": { "vo2max_ml_kg_min": 29.0, "resting_hr_bpm": 66, "sleep_hours": 7.2, "sri_0_100": 84, "hba1c_pct": 5.9, "waist_to_height": 0.56, "systolic_bp_mmhg": 138, "egfr_ml_min": 72, "grip_kg": 38, "strength_min_per_week": 60, "steps_per_day": 7400, "drinks_per_week": 12, "smoking_status": { "status": "former", "quit_age": 50 } } }, "expected": { "spec_version": "0.1.0-draft", "chronological_age": 67.0, "estimate": 72.6, "offset_years": 5.6, "range": [ 68.64, 76.56 ], "range_level": 0.8, "contributions_years": { "alcohol": 0.5, "egfr": 0.883, "glycemia": 0.774, "grip": 0.482, "resting_hr": -0.2, "sleep_duration": 0.0, "sleep_regularity": -0.943, "smoking": 4.779, "steps": -2.779, "strength_training": -1.886, "systolic_bp": 2.74, "vo2max": 0.202, "waist_to_height": 1.048 }, "domains_years": { "fitness": 0.202, "habits": 2.5, "heart": -0.2, "metabolic": 5.446, "sleep": -0.943, "strength": -1.404 }, "missing_key_signals": [] } }, { "id": "sparse-wearable-only", "note": "Only steps and resting HR: wide range, never pulled to calendar age.", "person": { "age": 33.0, "sex": "male", "inputs": { "steps_per_day": 11500, "resting_hr_bpm": 58 } }, "expected": { "spec_version": "0.1.0-draft", "chronological_age": 33.0, "estimate": 28.65, "offset_years": -4.35, "range": [ 24.44, 32.85 ], "range_level": 0.8, "contributions_years": { "resting_hr": -0.6, "steps": -3.754 }, "domains_years": { "habits": -3.754, "heart": -0.6 }, "missing_key_signals": [ "vo2max", "sleep_duration", "sleep_regularity", "glycemia", "waist_to_height", "systolic_bp", "egfr", "grip", "smoking", "alcohol" ] } }, { "id": "high-risk-clip", "note": "Many adverse values: offset is clipped at +15 years and contributions scaled.", "person": { "age": 50.0, "sex": "male", "inputs": { "vo2max_ml_kg_min": 18, "hrr_1min_bpm": 8, "resting_hr_bpm": 96, "night_resp_rate_per_min": 18, "sleep_hours": 5.2, "sri_0_100": 58, "hba1c_pct": 7.4, "waist_to_height": 0.68, "hs_crp_mg_l": 6, "systolic_bp_mmhg": 165, "egfr_ml_min": 40, "grip_kg": 28, "steps_per_day": 2200, "sedentary_hours": 12.5, "mvpa_min_per_day": 0, "drinks_per_week": 30, "smoking_status": "current" } }, "expected": { "spec_version": "0.1.0-draft", "chronological_age": 50.0, "estimate": 65.0, "offset_years": 15, "range": [ 61.42, 68.58 ], "range_level": 0.8, "contributions_years": { "alcohol": 0.874, "crp": 0.575, "egfr": 0.894, "glycemia": 0.927, "grip": 1.238, "hr_recovery": 0.659, "resp_rate": 0.187, "resting_hr": 0.253, "sedentary": 2.908, "sleep_duration": 0.192, "sleep_regularity": 0.806, "smoking": 2.321, "steps": 0.417, "systolic_bp": 1.331, "vo2max": 0.808, "waist_to_height": 0.611 }, "domains_years": { "fitness": 1.467, "habits": 6.52, "heart": 0.439, "metabolic": 4.339, "sleep": 0.998, "strength": 1.238 }, "missing_key_signals": [] } } ] }